[Impacts of airborne particulate matter and its components on respiratory system health]

Zhonghua Yu Fang Yi Xue Za Zhi. 2016 Dec 6;50(12):1114-1118. doi: 10.3760/cma.j.issn.0253-9624.2016.12.018.
[Article in Chinese]

Abstract

Nowadays, particulate air pollution has been a global environmental problem. Numerous studies has shown that long-term exposure to high level of airborne particulate matter (PM) can damage human health. Respiratory system, as a direct portal to contact with particulate matter, can be more susceptible to airborne particulates. Summarizing latest five-year epidemiological research, the present review is focused on the effects of PM on respiratory system health in different age groups. In detail, we investigated the harmful effect of PM, or its components on three common respiratory diseases, including lung function decline, chronic obstructive pulmonary disease (COPD) and asthma. The result showed that, to a certain degree, PM could induce the decline of lung function, the development and the exacerbation of COPD and asthma by oxidative stress and inflammatory reaction. And it may prompt that exposure to PM can be an improtant risk factor for the respiratory system health.

Publication types

  • Review

MeSH terms

  • Air Pollutants
  • Air Pollution / adverse effects*
  • Asthma / etiology*
  • Asthma / physiopathology
  • Epidemiologic Studies
  • Humans
  • Lung / drug effects
  • Lung / physiopathology*
  • Oxidative Stress
  • Particulate Matter / adverse effects*
  • Pulmonary Disease, Chronic Obstructive / etiology*
  • Pulmonary Disease, Chronic Obstructive / physiopathology
  • Respiratory System / physiopathology*
  • Risk Factors

Substances

  • Air Pollutants
  • Particulate Matter